IntegriCulture secures Niigata investment for cellular agriculture
Japanese cellular agriculture firm IntegriCulture has secured undisclosed investment from Niigata Venture Capital to accelerate development of food and cosmetic ingredients using local sake brewing byproducts.

IntegriCulture has secured investment from Niigata Venture Capital's Regional Revitalization Fund to accelerate development of cosmetic raw materials and food products. The Japanese cellular agriculture company, headquartered in Tokyo, closed the funding from the Regional Revitalization Niigata Fund No. 2 on October 28. The company plans to use the capital to speed up cosmetics ingredient development and product launches, expand its regional implementation network, strengthen sales, and develop its core technology. Cosmetic raw materials are a priority to generate income earlier in the commercialization process.
Regional partnerships drive cell agriculture
In Niigata Prefecture, IntegriCulture works with local food company Ichimasa Kamaboko and Tsunan Sake Brewery. The company has a joint R&D agreement with Tsunan Sake Brewery to prototype cell-cultured food and cosmetic ingredients using the brewery's natural water. Niigata's brewing and fermentation industry is unusually well suited to cell agriculture. This is due to underused resources like sake lees, decades of process know-how, and local partners ready to build something new together. IntegriCulture is working with these regional partners to connect cell cultivation with existing local resources and production knowledge. The company's approach spans applications in food, cosmetics, and materials.
Technology and production milestones
IntegriCulture supplies culture media, equipment and contract development to businesses working with cultivated cells. Its CulNet System produces growth components inside the culture setup. In 2022, the company reported cultivating cells without animal serum at an estimated one-sixtieth of the cost of conventional serum. The company is advancing partnerships with firms like Sumitomo Riko and Oisix ra daichi. In March, the companies announced a strategic partnership covering avian cell production demonstrations in Singapore and plans for a domestic contract manufacturing service in Japan.
That work uses the Oxy-thru Cultivator, a two-liter cell-culture bag developed within IntegriCulture's CulNet Consortium. Sumitomo Riko and IntegriCulture reported production of one kilogram per month per bag, including scaffolds. This uses Sumitomo Riko's gas-permeable materials and precision molding technology. The bag is designed to operate inside an incubator without equipment injecting oxygen directly into the culture. This supports production through multiple small units with potential benefits for operating flexibility and costs.
Leadership shift toward commercial rollout
A management change in July has separated domestic technology development from overseas expansion. This supports the company's transition from research and development toward wider commercial implementation. Responsibility for advancing IntegriCulture's domestic technology and production activities now sits with CTO Ikko Kawashima. Ikko Kawashima became a representative director alongside CEO Yuki Hanyu. Hanyu took responsibility for developing overseas opportunities and overseeing international expansion.
IntegriCulture also develops its own ingredients for food and cosmetics. The company's expansion of regional partnerships and acceleration of cosmetic ingredient development marks its latest step toward commercialization.





